Abstract
A variety of 3,5–diaryl–6-carbethoxy cyclohex-2-en-1-ones derivatives (4a-g) were synthesized by the reaction of ethylacetoacetate with substituted chalcones in conventional(acetone & anhy. K 2CO3) and microwave assisted solution phase (acetone & anhy. K 2CO3) and dry media (basic Al 2O3/piperidine). From the comparative study wehave concluded that efficient dry media synthesis of 3,5–diaryl–6-carbethoxy cyclohex-2-en-1-ones under microwave irradiation can be carried out in domestic microwave oven with enhanced reaction rates and improved yields.The structure of compounds are supported by spectral and analytical data. The structure activity relationship of synthesized compounds have also been studied.
